Verified guide
Minimally invasive
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PRP en España: Guía de Plasma Rico en Plaquetas, Precios y Clínicas Verificadas

Natural regeneration powered by your own blood

Table of contents

What is PRP – Platelet-Rich Plasma?

Definition and how it works

PRP (Platelet-Rich Plasma) is an autologous regenerative therapy that uses the patient's own blood. A small blood sample is drawn, centrifuged to concentrate the platelets (5–10 times the normal concentration) and the resulting plasma — rich in growth factors — is reinjected into the target area. Growth factors (PDGF, TGF-β, VEGF, EGF) stimulate cellular regeneration and new tissue formation.

Origin and history

PRP was developed in haematology in the 1970s for transfusions. Its use in oral surgery began in the 1990s and expanded to sports and aesthetics from 2006 onwards, after several elite footballers popularised it for treating serious injuries.

Benefits of PRP – Platelet-Rich Plasma

Soft tissue and cartilage regeneration

Non-surgical facial and hair rejuvenation

Reduction of chronic joint pain (knee, shoulder, hip)

Accelerated healing of sports injuries

Stimulation of hair growth in androgenic alopecia

Improved skin texture and radiance

PRP – Platelet-Rich Plasma protocol step by step

1

Blood draw

15–60 ml of peripheral venous blood drawn (identical to a standard blood test).

2

Centrifugation

Centrifuged at 2,500–3,000 rpm for 10–15 min to separate platelet-rich plasma.

3

Activation (optional)

Activation with calcium chloride or thrombin to release growth factors.

4

Injection

Guided application (ultrasound/fluoroscopy) to target area under local anaesthesia.

5

Post-treatment

Relative rest for 24–48 hours. Avoid NSAIDs. Follow-up at 4–6 weeks.

Reference equipment for PRP – Platelet-Rich Plasma

EquipmentBrand / Model
Double-spin medical centrifugeHarvest SmartPreP / Arthrex ACP
Ultrasound guidanceGE Logiq / Mindray

Clinics on LongevityMap declare their exact equipment for objective scoring.

The science behind PRP – Platelet-Rich Plasma

Scientific evidence summary

Over 10,000 published studies support PRP. Meta-analyses in the American Journal of Sports Medicine confirm its superiority over hyaluronic acid for knee osteoarthritis at 12 months. In dermatology, controlled trials show 35–40% increases in hair density after 3 sessions. Platelet concentration and the activation protocol are critical quality factors.

Key published studies

PRP versus hyaluronic acid for knee osteoarthritis: meta-analysis

American Journal of Sports Medicine · 2021

PRP superior to HA at 12 months for pain reduction and functional improvement in knee osteoarthritis.

PubMed

Platelet-rich plasma for androgenic alopecia: RCT

Journal of the American Academy of Dermatology · 2019

35–40% increase in hair density after 3 sessions versus placebo.

PubMed

How much does PRP – Platelet-Rich Plasma cost in Spain?

Price per session

€150–350 per session

3 sessions (4 weeks apart); annual maintenance

Prices vary by clinic, equipment and practitioner experience. LongevityMap compares price and quality so you always make the best decision.

How we calculate prices

Who is PRP – Platelet-Rich Plasma for?

Recommended profiles

  • 1People with osteoarthritis or chronic tendon injuries
  • 2Athletes with musculotendinous injuries
  • 3People with early or moderate androgenic alopecia
  • 4Those seeking natural facial rejuvenation
  • 5Post-surgical recovery patients

Precautions and contraindications for PRP – Platelet-Rich Plasma

Main contraindications

  • Thrombocytopenia or coagulation disorders
  • Active infection at the injection site
  • Anticoagulant therapy (requires medical evaluation)
  • Active cancer in the treated area

Treatments that combine with PRP – Platelet-Rich Plasma

PRP – Platelet-Rich Plasma shows scientific synergy with these treatments:

Comparisons for PRP – Platelet-Rich Plasma

Where to get PRP – Platelet-Rich Plasma in Spain?

Compare PRP – Platelet-Rich Plasma clinics across Spain's main cities. Each page includes local prices, quality scores and verified rankings.

Frequently asked questions about PRP – Platelet-Rich Plasma

Is PRP painful?
Topical or local anaesthesia is applied before injections. The blood draw is identical to a standard blood test. Post-procedure discomfort is mild and lasts 1–2 days.
When will I see results from hair PRP?
Initial results (reduced hair loss) are visible at 2–3 months. Visible new hair growth is typically observed between 4 and 6 months after starting the protocol.
Is there any risk of rejection with PRP?
No, because the patient's own blood is used. The risk of allergic reaction or rejection is virtually nil, making PRP one of the safest regenerative therapies available.

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Content created by the LongevityMap editorial team based on peer-reviewed scientific literature. Sources: PubMed, Cochrane Library. This content does not replace professional medical advice. Our team · Methodology