3 forms with radically different bioavailability · crystalline is marketing if you want clinical effects · phytosome or EMIQ is mandatory.
Patented phosphatidylcholine phytosome
Best for
Ideal use: DQ+F senolytic stack protocol, COVID prophylaxis, endothelial FMD.
Advantages
Bioavailability ~20x crystalline (Riva 2019). Form used in Di Pierro COVID RCT + Mayo senolytic. Standardized 250 mg quercetin/capsule.
Disadvantages
Expensive (~25-50 €/month at 500 mg). Only in premium brands paying Indena royalty.
Hayashibara JP · α-glycosyl isoquercitrin
Best for
Ideal use: seasonal allergy, asthma, cross gluten-mast-cell sensitivity.
Advantages
Bioavailability ~17-25x crystalline via glycosyl-conjugate absorbed efficiently. Form used in Yamada 2024 allergy RCT.
Disadvantages
Less availability in Spain · more common JP/USA. Different taste (slightly sweet).
Vanilla 95% pure flavonoid
Best for
Ideal use (limited): chronic flavonoid-stack supplement, NOT for senolytic pulse protocol.
Advantages
Economical (~10-20 €/month at 500 mg). Good for concentrated source in flavonoid-rich diet-augmenting stack.
Disadvantages
Oral bioavailability ~1-2% · unlikely to reach senolytic plasma concentrations (~1-10 µM) except impractical doses >3 g/day. For senolytic: insufficient.
Ideal use: DQ+F senolytic stack protocol, COVID prophylaxis, endothelial FMD.
Ideal use: seasonal allergy, asthma, cross gluten-mast-cell sensitivity.
Ideal use (limited): chronic flavonoid-stack supplement, NOT for senolytic pulse protocol.
3 forms with radically different bioavailability · crystalline is marketing if you want clinical effects · phytosome or EMIQ is mandatory.